When your immune system seems to be working against you, this is where we start — a focused, targeted look at autoimmune activity and systemic inflammation.
Unlike large functional testing programs where results are reviewed by an unknown provider on a team, you know exactly who is interpreting your labs. Autoimmune conditions are among the most underdiagnosed in medicine — patients often spend years collecting symptoms before the underlying immune activity is identified. This panel is designed to cut through that timeline.
This panel is focused by design — thirteen biomarkers specifically chosen to identify autoimmune activity, systemic inflammation, and immune dysfunction. If you've already completed a foundational workup, this panel adds the targeted autoimmune layer.
The primary screening test for systemic autoimmune disease including lupus, Sjögren's, scleroderma, and mixed connective tissue disease. If positive, automatically reflexes to titer and pattern for deeper characterization.
Measures how quickly red blood cells settle, reflecting the presence and degree of systemic inflammation — a simple but meaningful marker of active immune activity.
Celiac is one of the most commonly missed autoimmune conditions. This screens for tissue transglutaminase antibodies, endomysial antibodies, and total IgA — a comprehensive approach rather than a single marker.
Tests for Hashimoto's thyroiditis, the most common autoimmune condition in women. Antibodies can be elevated for years before thyroid function is affected — catching this early allows for intervention before damage accumulates.
Tests for Graves' disease autoimmunity. Together with thyroid antibodies, this gives complete coverage of both ends of autoimmune thyroid disease.
A highly specific marker for systemic lupus erythematosus (SLE). Elevated levels strongly suggest active lupus and correlate with disease activity.
Complement proteins are consumed during active immune responses. Low C3 and C4 in the context of a positive ANA or ds-DNA is a hallmark of lupus activity and helps assess disease severity.
Anyone with a known or suspected autoimmune condition, unexplained joint pain, fatigue, skin changes, dry eyes or mouth, recurring illness, or digestive issues. Also ideal for anyone with a strong family history of autoimmune disease who wants proactive screening.
Click the button below. You'll be taken to Fullscript — the secure platform I use for lab ordering. Enter your email and zip code to confirm a Quest Diagnostics location near you, create a free account if you don't have one, and complete checkout. Takes about two minutes.
With over 2,000 Quest Diagnostics locations nationwide, there's almost certainly one near you. No separate lab appointment needed — walk in at your convenience.
Once your results are available, I review every biomarker using functional ranges. You receive plain-language interpretation and a personalized wellness plan — not just a number on a page with no context.
13 biomarkers. Personally reviewed. A clear roadmap — not just a result.
Order Your Panel — $349 HSA & FSA eligible · Quest Diagnostics nationwide · Reviewed by Dr. BarbieNot sure if this is the right panel for you? A 15-minute phone consultation is available for $75 — schedule here.